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Shoulder/ Rotator cuff injury 

Rotator cuff injuries, typically caused by a combination of factors, can significantly impact a patient's quality of life. Overuse or repetitive stress, common in certain sports or job activities, along with aging and degenerative changes, contribute to the vulnerability of the rotator cuff tendons. Trauma, such as falls or direct blows to the shoulder, can also lead to tears in the rotator cuff.

The mechanism of these injuries involves impingement, where the rotator cuff tendons are compressed between the humeral head and the acromion during overhead arm movements. Tendon degeneration, characterized by the gradual breakdown of tissue, and acute or chronic tears further contribute to the complexity of rotator cuff injuries.

Patients with rotator cuff injuries often experience persistent shoulder pain, both during arm movements and at rest. The limited range of motion, especially in activities like reaching overhead or behind the back, becomes apparent. This impaired functionality extends to daily tasks such as lifting objects, dressing, and participating in sports or recreational activities. Additionally, sleep disturbances may occur as pain interferes with the ability to find a comfortable sleeping position.

Rotator cuff tears have conventionally been addressed through surgical interventions aimed at repairing the damaged tendons, with the goal of enhancing function and alleviating pain. However, the effectiveness of surgery in achieving long-term success has been a subject of debate. Numerous studies suggest that even with advancements in surgical techniques and materials, there remains a persistently high failure rate ranging from 30% to 94% for tendon-to-bone rotator cuff repairs.

The primary challenge underlying the failure of rotator cuff repair appears to be biologic. The intricate fibro-cartilaginous transition zone between the rotator cuff and the bone lacks the capacity for regeneration after standard repair techniques. Instead, these techniques often result in the formation of fibro-vascular scar tissue with suboptimal mechanical properties.

Recognizing this limitation, current research focus has shifted from solely improving mechanical aspects of repair to enhancing the biological environment surrounding the repair site. This entails exploring the potential of biological therapies such as growth factors (GF), bone morphogenetic proteins (BMPs), and, notably, stem cells. The hypothesis is that these biological interventions may promote the regeneration of the normal tendon-to-bone insertion microarchitecture while limiting the formation of scar tissue.

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Mesenchymal stem cell treatment for shoulder /rotator cuff 

Stem cell treatment for shoulder pain has emerged as a promising avenue in the quest for effective and sustainable solutions. The shift in research focus from purely mechanical enhancements of repair techniques to improving the biological environment surrounding the repair underscores the potential of stem cells in this domain.

The research paradigm has expanded to include biological therapies such as growth factors (GF), bone morphogenetic proteins (BMPs), and notably, stem cells. The overarching hypothesis is that these biological interventions can play a pivotal role in facilitating the regeneration of the normal tendon-to-bone insertion microarchitecture while simultaneously limiting the formation of scar tissue—a common challenge in traditional repair approaches.

In recent explorations, isolated growth factors (GF) or platelet-rich plasma have been employed, yielding variable results. However, stem cells stand out as a more promising alternative in the pursuit of enhanced therapeutic outcomes for shoulder pain. Stem cells, renowned for their regenerative potential, have demonstrated significant influence in promoting angiogenesis and modulating inflammatory patterns within the healing process.


The unique capacity of stem cells to positively impact the biologic aspects of healing positions them as a valuable candidate for addressing shoulder pain. As research advances, the application of stem cell therapies holds great promise in not only mitigating pain but also fostering a more biologically conducive environment for the optimal healing of shoulder injuries.

At Revival Clinic, our ankle stem cell treatment involves a straightforward intraarticular injection of mesenchymal stem cells derived from umbilical cord tissue. This targeted approach is designed to harness the regenerative potential of these cells for intraarticular pathology within the shoulder.

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Had been thinking about getting Stem Cell therapy for many years now but couldn’t find the right place. But all was answered after getting in touch with Revival.


I spoke to George and we came up with a plan to help increase mobility and decrease the severe pain in my ankle.


He was brilliant along with all the staff, they all made me feel very comfortable and at ease during the procedure. It was swift and simple. I’m already feeling a big difference!


I’m glad I took the leap of faith and came to Revival for my treatment!

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Our patient story 

We are excited to share the success story of a recent patient, highlighting the effectiveness of stem cell treatment as a promising option for shoulder issues. Alex, a vibrant man in his early 40s, fueled by his passion for tennis, found himself grappling with the aftermath of multiple rotator cuff injuries. Despite undergoing arthroscopic surgery, the relief he sought remained elusive, leaving him with a lingering shoulder issue that subtly but persistently disrupted his quality of life.

Facing the prospect of a second surgery, Alex, motivated by his previous experience and a desire for an alternative, delved into extensive research. His quest for a solution led him across continents, as he decided to fly from Canada to explore stem cell treatment at our clinic.

The injection procedure, a key part of our advanced stem cell therapy, went seamlessly. Alex's journey took an unexpected turn as the results surpassed his expectations. Not only did he experience a notable improvement, but the outcomes of the stem cell treatment exceeded those of his previous surgery. What's more, the approach was notably more cost-effective, less complicated, and offered a smoother recovery process.

Alex's success story stands as a testament to the transformative potential of stem cell treatment for shoulder issues. Beyond merely alleviating pain, this innovative approach has the capacity to enhance the overall quality of life, providing individuals like Alex with a viable alternative to conventional surgical interventions. His decision to explore stem cell treatment reflects a growing trend where patients seek effective, minimally invasive, and cost-conscious solutions for their health concerns. At our clinic, we take pride in being a part of Alex's journey and in offering cutting-edge treatments that empower individuals to reclaim their lives from the grip of persistent shoulder pain."

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