Male Hormone Panel

This comprehensive blood test panel evaluates key hormones that regulate male reproductive and overall health. It provides insights into testosterone status, pituitary function, estrogen balance, and hormone binding capacity, all of which are crucial for energy levels, libido, muscle mass, fertility, mood, and general well-being.

Who Should Get Tested?

This panel is recommended for men who experience symptoms such as:

Low libido or erectile dysfunction
Fatigue or low energy
Decreased muscle mass or increased body fat
Infertility or low sperm count
Mood changes such as irritability or depression
Gynecomastia (male breast development)
Hair loss
Difficulty concentrating (“brain fog”)

It is also useful for monitoring men undergoing testosterone replacement therapy or those evaluating fertility or hormone-related conditions.

Did you know male hormone imbalance can start earlier than you think?

Men can start experiencing male hormone imbalances as early as their late 20s to early 30s, but it becomes more common after age 40 due to natural aging and lifestyle factors.

Here's a general timeline:

🔹 Ages 20–30s

Rare, but imbalance can occur due to:
- Anabolic steroid use
- Pituitary disorders
- Obesity or extreme stress
- Genetic or congenital issues (e.g. Klinefelter syndrome)
Symptoms may include low libido, fatigue, infertility, or mood swings.

🔹 Ages 40+

Testosterone levels naturally decline about 1% per year after age 30–35.
Common signs of imbalance begin here:
- Decreased energy and libido
- Erectile dysfunction
- Increased fat, especially around the abdomen
- Mood changes and sleep issues

🔹 Ages 50–60+

Many men experience noticeable symptoms of andropause (age-related testosterone decline).
More common to require medical evaluation and possible testosterone therapy if quality of life is affected.

Factors That May Cause Earlier Imbalance:

Poor sleep
High stress or cortisol levels
Sedentary lifestyle
Poor diet or excess alcohol
Medical conditions (e.g., diabetes, thyroid issues)

ADAM Questionnaire

1. Do you have a decrease in libido (sex drive)?
2. Do you have a lack of energy?
3. Do you have a decrease in strength and/or endurance?
4. Have you lost height?
5. Have you noticed a decreased "enjoyment of life"?
6. Are you sad and/or grumpy?
7. Are your erections less strong?
8. Have you noticed a recent deterioration in your ability to play sports?
9. Are you falling asleep after dinner?
10. Has there been a recent deterioration in your work performance?

🔎 How to interpret:

If a man answers “Yes” to questions 1 or 7, or any 3 other questions, it may suggest possible low testosterone, and further blood tests (like your Male Hormone Panel) are warranted.

Total Testosterone

Function: The primary male sex hormone responsible for libido, muscle mass, bone density, red blood cell production, and overall vitality.
Target Range: 300–1000 ng/dL (may vary slightly by lab)
Low Levels May Indicate: Hypogonadism, pituitary dysfunction, chronic illness, or obesity.
Symptoms of Low T: Fatigue, low sex drive, muscle loss, erectile dysfunction.
High Levels May Be From: Testosterone therapy, anabolic steroids, or tumors (rare).

Free Testosterone

Function: The biologically active portion of testosterone, not bound to proteins like SHBG.
Target Range: 5–20 ng/dL
Low Free T With Normal Total T: Often caused by high SHBG; symptoms can still occur despite “normal” total T.
High Levels: Typically seen with testosterone therapy.

SHBG

Sex Hormone Binding Globulin

Function: Binds to testosterone, controlling its availability. Only free testosterone is active.
Target Range: 10–57 nmol/L
High SHBG: Reduces free testosterone; common in aging, hyperthyroidism, or liver disease.
Low SHBG: Increases free testosterone; often seen in obesity, hypothyroidism, insulin resistance.

FSH

Follicle-Stimulating Hormone

Function: Regulates sperm production by stimulating the testes.
Target Range: 1.5–12.4 mIU/mL
Low FSH: May indicate pituitary suppression from hormone replacement or Pituitary damage.
High FSH: May reflect testicular failure or damage.
Symptoms: Abnormal sperm production, infertility.

LH

(Luteinizing Hormone)

Function: Stimulates testosterone production in the testes.
Target Range: 1.7–8.6 mIU/mL
Low LH: May indicate pituitary dysfunction, pituitary suppression from hormone replacement
High LH: Often seen when the testes fail to respond, causing a feedback loop.
Symptoms: Low testosterone symptoms due to inadequate stimulation.

Progesterone

Function: Supports testosterone synthesis and helps balance estrogen effects.
Target Range (male): <1 ng/mL (commonly 0.1–0.6 ng/mL)
Low Levels: May be associated with estrogen dominance, sleep problems, anxiety, excessive use of testosterone. Low progesterone in men may cause anxiety, poor sleep, low libido, brain fog, fatigue.
High Levels: Rare, may be due to supplementation or adrenal tumors.

E2

Estradiol

Function: A form of estrogen important for libido, bone health, and mood; normally present in low levels in men.
Target Range: 10–40 pg/mL
High E2: often caused by obesity, excess testosterone therapy, Can cause gynecomastia, water retention, mood swings, and low libido. Often due to obesity, liver issues, or aromatization of testosterone.
Low E2: may result from overuse of aromatase inhibitors to treat high E2, low body fat, or low testosterone. This can cause joint pain, bone loss, low mood, and reduced sexual desire.

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