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mycobacterium infection of skin

mycobacterium infection of skin

  1. tuberculosis

  2. non tuberculosis : do not transmits from human to human , usually resistance to anti-TB drug

clinical mycobacterium tuberculosis

  1. tuberculous chancre : undermined edge , no pain , chronic ulcer , lymphadenopathy [rare]

  2. acute miliary TB : usually in children after fever with rash , red [macule , papule , vesicle , purpura ]with central necrosis  click for picture 

  3. Lupus vulgaris [endogenous or exogenous transmission ]solitary brown apple jelly [diascopic ]plaque smooth surface or mild scale click for picture

  4. tuberculosis verrucosa cutis : exogenous , solitary erythematous rough plaque with crust and pus click for picture 

  5. scrofuloderma : endogenous , painless hard nodule then soft and rupture in to pus drainage sinus tract click for picture 

  6. papulonecrotid tuberculid : dark red papule with central necrosis , leave atrophic scar  click for picture 

  7. lichen scrofurosum : lichenoid eruption minute papule click for picture 

  8. erythema induratum : dark red nodule and papule click for picture 

laboratory

  1. skin biopsy + AFB

  2.  tuberculin skin test

  3. tissue culture [NMT culture on Lowenstein Jasen media ] [8 weeks ]

  4. PCR more rapid more specific

medication

  1. TB : 9 month IRZE

  2. NTB : depend on sensitivity

  3. cryotherapy

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